Proscar

Proscar, whose active ingredient is finasteride, is also known by alternative names such as Propecia. It is used primarily to treat and manage symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). By reducing the size of the prostate gland, Proscar helps in improving urinary flow and may reduce the need for surgery related to prostate issues. It is prescribed to adult men experiencing these particular health concerns. This medication functions by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), which is a key factor in prostate growth. Understanding its purpose can help those affected seek the appropriate medical advice.

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Proscar Price Info

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The cost of the Proscar varies from £0.84 to £1.49 per pills. It depends on the size of the pack and the amount of active ingredient (30 or 360 mg).

Drug Classification and Use

Proscar is classified as a 5-alpha-reductase inhibitor. It is primarily used for the treatment of benign prostatic hyperplasia (BPH) in men. By inhibiting the conversion of testosterone to dihydrotestosterone (DHT), Proscar helps in reducing the size of an enlarged prostate, improving symptoms such as difficulty urinating, decreased urinary flow, and the need for surgery.

Dosage and Administration Guidelines

The recommended dose of Proscar is one 5 mg tablet taken orally once daily, with or without food. It is important that patients adhere to the prescribed dosage and schedule as advised by their healthcare provider. The effects of the medication may not be immediately noticeable, and it may require consistent use over several months to achieve optimal results.

Mechanism of Action

Proscar works by inhibiting the enzyme 5-alpha-reductase. This enzyme is responsible for converting testosterone into the more potent androgen, DHT. By reducing DHT levels, Proscar helps shrink the prostate and relieve urinary obstruction, thereby alleviating symptoms of BPH. This biochemical action is specific to the drug’s therapeutic effect without affecting circulating testosterone levels significantly.

Pharmacokinetic Properties

Proscar is efficiently absorbed through the gastrointestinal tract after oral administration. It has a bioavailability of approximately 80%. Peak plasma concentrations are achieved within 1-2 hours after dosing. The drug is extensively metabolized in the liver by cytochrome P450 3A4 enzymes into inactive metabolites, and it has a plasma elimination half-life of roughly 6-8 hours in adults. Excretion occurs primarily through the urine and feces.

Potential Drug Interactions

Proscar has been reported to interact with certain medications, though clinically significant drug interactions are rare. Co-administration with other 5-alpha-reductase inhibitors or drugs affecting hepatic enzyme activity should be approached cautiously. It is advisable for patients to inform their healthcare providers of all medications they are taking, including over-the-counter drugs and supplements, to prevent potential interactions.

Adverse Effects and Management

Some common adverse effects associated with Proscar include decreased libido, erectile dysfunction, and ejaculation disorder. These sexual side effects may diminish with continued treatment. Gynecomastia has also been observed in a small percentage of patients. If serious adverse effects occur or persist, patients should consult their healthcare provider to discuss alternative treatment options or symptomatic management strategies.

Considerations for Special Populations

Proscar is intended solely for male patients, particularly those with BPH. It should not be used by women, especially during pregnancy, due to the risk of fetal harm. Additionally, caution should be exercised in patients with hepatic impairment, as the drug is metabolized in the liver. Adjustments in the dosing regimen may be necessary for patients with significant liver dysfunction to prevent accumulation and potential toxicity.

Storage and Stability

Proscar tablets should be stored at room temperature, between 15°C to 30°C (59°F to 86°F), away from moisture and heat. They should remain in their original packaging to protect from light and to maintain stability. Expired or unused medication should be disposed of in accordance with local regulations to ensure environmental safety.

Patient Counseling Points

When counseling patients on Proscar, it is important to emphasize adherence to prescribed dosages and the importance of regular medical follow-ups to monitor prostate-specific antigen (PSA) levels and overall therapeutic outcomes. Patients should be informed about the potential side effects and instructed to report any unusual changes promptly. Additionally, they should be advised against the donation of blood while on Proscar, and for at least six months after treatment, to prevent administration to a pregnant transfusion recipient.

Dosage

5mg

Active ingredient

Finasteride

Pack

120 pills, 180 pills, 270 pills, 30 pills, 360 pills, 60 pills, 90 pills

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Proscar
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